(R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid is an organic compound with the chemical formula C18H17FNO4. The following are relevant properties, uses, methods and safety information:
Nature:
-Appearance: White crystalline solid
-melting point: about 130-132 ℃
-Solubility: Soluble in common organic solvents
-Chemical properties: The compound is an amino acid derivative with acidic and acidic functional groups. It can undergo esterification and aminolysis reactions with other compounds.
Use:
-Pharmaceutical Field:(R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid is a kind of amino acid derivatives, which may have potential pharmaceutical activity. It may be used as a drug molecule or as a raw material for the synthesis of other drugs.
Preparation Method:
- (R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid can be prepared in a variety of ways, the following is a brief step of one of the synthetic routes:
1. Benzyl alcohol reacts with dimethylformamide to give the corresponding etherate of benzyloxy dimethylformamide.
2. The corresponding alcohols and carbonyl compounds were prepared by nucleophilic addition reaction of dimethylformamide etherate and 2-fluoroacetophenone.
3. Finally, the hydroxyl compound produced by the carbonylation reaction is condensed to obtain the final product (R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid.
Safety Information:
The safety of- (R)-2-(((Benzyloxy)carbonyl)amino)-3-(2-fluorophenyl)propanoic acid has not been fully studied, so its use and handling should consider appropriate safe operating procedures.
-When used under laboratory conditions, appropriate personal protective equipment should be used, such as gloves and safety glasses.
-This compound should be stored in a dry, well-ventilated place, away from fire and oxidizing agents. Avoid inhalation, ingestion or contact with skin and eyes.
-When using or handling this compound, you should follow the relevant safety operating procedures and refer to the safety data sheet of the chemical according to the actual situation. If there is any doubt or uncertainty, it is recommended to consult a professional.